Journal Title
Title of Journal: Arch NeurPsych
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Abbravation: Archives of Neurology & Psychiatry
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Publisher
American Medical Association
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Authors: HOWARD H BEARD ERNEST J JACOB
Publish Date: 1939/07/01
Volume: 42, Issue: 1, Pages: 67-82
Abstract
Folin1 as a result of his classic studies on protein metabolism in 1905 came to the conclusion that the daily creatinine output of a given person is more or less constant is influenced by the body weight and is independent of a diet which does not contain creatine or creatinine At this time he introduced the term creatinine coefficient which may be defined as the amount in milligrams of creatinine or creatinine nitrogen excreted daily per kilogram of body weight Also since the excretion of creatinine is independent of the diet it is considered to represent the endogenous metabolism of the body as compared to the excretion of urea which represents the exogenous metabolism In Shaffers2 view the output of creatinine represents not necessarily the endogenous metabolism but only one special phase thereof which takes place largely if not wholly in the muscles This view was later adopted
Keywords:
References
citation title=A Study of Muscle Chemistry in Myasthenia Gravis Pseudohypertrophic Muscular Dystrophy and Myotonia citation author=Nevin SBrain citation year=1934 citation volume=57 citation pages=239
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