Journal Title
Title of Journal: AMA Arch Surg
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Abbravation: A.M.A. Archives of Surgery
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Publisher
American Medical Association
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Authors: CHARLES W McLAUGHLIN JOHN D COE
Publish Date: 1954/09/01
Volume: 69, Issue: 3, Pages: 378-384
Abstract
THE CLINICAL significance of acute and chronic thrombocytopenic purpura has been well understood for many years The simultaneous occurrence of such a condition during the immediate postoperative period presents additional problems which require prompt recognition and careful treatment Our recent experience with seven such cases has focused our attention on this particular problemThe function of the platelets in circulating blood was recognized and described by Bizzozero in 1882 He demonstrated their adhesive qualities participation in thrombi and the role in the coagulation of blood The actual origin of these platelets has been the subject of much speculation but Wright in 1906 suggested that they were formed in the bone marrow from megakaryocytes He concluded that the platelets represented detached bits of cytoplasm of the megakaryocytes9 There are roughly 100000 of these platelets formed and destroyed each day and the entire number in the circulating plasma can be replaced
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References
citation title=Surgical Aspects of Hypersplenism citation author=Zollinger R M Martin M M and Williams R DJ A M A citation year=1952 citation volume=149 citation pages=2429
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