Journal Title
Title of Journal: AMA Arch Ophthalmol
|
Abbravation: A.M.A. Archives of Ophthalmology
|
Publisher
American Medical Association
|
|
|
|
|
|
Authors: HARRY GREEN STANLEY A CAPPER CAROL A BOCHER IRVING H LEOPOLD
Publish Date: 1954/11/01
Volume: 52, Issue: 5, Pages: 758-762
Abstract
THE DRAMATIC effect of acetazoleamide Diamox 2acetylamino134thiadiazole5sulfonamide a potent carbonic anhydrase inhibitor in lowering intraocular pressure has focused attention upon the possible role of the enzyme in the secretory mechanism of the ciliary body and iris This association is particularly suggestive in view of the report by Wistrand2 of the presence of carbonic anhydrase activity in the ciliary body and iris of the rabbit eye It was deemed of fundamental importance therefore to determine whether the administration of acetazoleamide affected the carbonic anhydrase activity of the ciliary body and irisMETHODS Carbonic anhydrase activity was measured in a Warburg apparatus at 1 to 2 C according to the method of Krebs and Roughton3 The amount of blood in the tissue was determined with the benzidine reaction according to Ashby and Chan4 Known dilutions of venous blood drawn from the same rabbit from which the tissue in question
Keywords:
References
citation title=Reaction of Cytochrome Oxidase with Cyanide citation author=Ball E GJ Biol Chem citation year=1952 citation volume=198 citation pages=629
.
|
Other Papers In This Journal:
|