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Publisher
Springer, Boston, MA
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Authors: J David Robertson
Publish Date: 1987
Volume: , Issue: , Pages: 3-24
Abstract
It is generally recognized that biological membranes have a common basic lipid bilayer structure1–5 which contains external internal and transmembrane proteins6 with chemical asymmetry as a fundamental feature7 8 the asymmetry involves both lipids and proteins see Rothman and Lenard9 and Robertson10 11 for recent reviews Certain glycoproteins such as glycophorin in erythrocyte membranes12 13 are arranged with a protein moiety in the internal leaflet connected to a glycoprotein moiety in the external leaflet14 In the case of glycophorin the internal and external parts are connected by a stretch of hydrophobic amino acid residues traversing the bilayer probably as an α helix
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