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Publisher
Springer, Berlin, Heidelberg
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Authors: Stefan Wagenpfeil Uwe Treiber Antonie Lehmer
Publish Date: 2003/10/9
Volume: , Issue: , Pages: 47-54
Abstract
Isobologram analysis is a way of exploring and visualizing combined drug effects The aim of this work is to determine as to whether two agents can be considered synergistic or antagonistic Resulting from a clinical consulting case in urology we developed a MATLABbased software tool for automated isobologram analysis In this way we supplement the clinical softwareequipment in our laboratory and encourage the evaluation of combined doseresponse experiments Analysis of an example data set demonstrates the approach and the way of interpreting obtained results
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