Immunobiology of the Torque Teno Viruses and Other

Authors: F Maggi M Bendinelli

Publish Date: 2009

Volume: , Issue: , Pages: 65-90

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Abstract

Many features of the Torque teno virus and the other anelloviruses AVs that have been identified after this virus was discovered in 1997 remain elusive The immunobiology of the AVs is no exception However evidence is progressively accumulating that at least some AVs have an interesting interplay with cells and soluble factors known to contribute to the homeostasis of innate and adaptive immunity Evidence is also accumulating that this interplay can have a significant impact on how effectively an infected host can deal with superimposed infectious and noninfectious noxae This review article discusses the scanty information available on these aspects and highlights the ones that would be more urgent to precisely understand in order to get an adequate assessment of how important for human health these extremely ubiquitous and pervasive viruses really are

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