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Publisher
Springer, Dordrecht
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Authors: Po Sing Leung
Publish Date: 2010
Volume: , Issue: , Pages: 109-130
Abstract
Cell culture system studies complement animal studies providing an indispensable tool for examining the underlying signalling mechanisms by which certain physiological responses are evoked and at the same time allowing observation to be attributed to distinct individual treatment factor They are often applied as primary screenings of the potential effects of certain drug treatment prior to further animal studies Experiments utilizing pancreatic cell lines or primary pancreatic cell cultures have been widely reported The term cell line generally refers to an immortalized group of cells originally derived from a single clone which can be in principle maintained permanently and proliferated upon exposure to appropriate medium in vitro Many cell lines are derived from abnormal tissues such as cancer specimens or tumour cells
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