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Publisher
Springer, New York, NY
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Authors: Jacob Beal Andrew Phillips Douglas Densmore Yizhi Cai
Publish Date: 2011
Volume: , Issue: , Pages: 225-252
Abstract
In electronic computing highlevel languages hide much of the details allowing nonexperts and sometimes even children to program and create systems High level languages for biomolecular systems aim to achieve a similar level of abstraction so that a system might be designed on the basis of the behaviors that are desired rather than the particulars of the genetic code that will be used to implement these behaviors The drawback to this sort of highlevel approach is that it generally means giving up control over some aspects of the system and having decreased efficiency relative to handtuned designs Different languages make different tradeoffs in which aspects of design they emphasize and which they automate so we expect that for biology there will be no single ‘right language’ just as there is not for electronic computing Because synthetic biology is a new area no mature languages have yet emerged In this chapter we present an indepth survey of four representative languages currently in development – GenoCAD Eugene GEC and Proto – as well as a brief overview of other related highlevel design tools
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