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Title of Journal: Clin J Gastroenterol

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Abbravation: Clinical Journal of Gastroenterology

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Springer Japan

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DOI

10.1007/s15006-012-1374-7

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1865-7265

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Extensive 0IIc undifferentiated carcinoma lesio

Authors: Yusuke Horiuchi Junko Fujisaki Tomoki Shimizu Hirotaka Ishikawa Yasumasa Matsuo Natsuko Yoshizawa Takanori Suganuma Kiyohisa Dan Masami Omae Akiyoshi Ishiyama Toshiaki Hirasawa Yorimasa Yamamoto Tomohiro Tsuchida Etsuo Hoshino Masahiro Igarashi Naoki Hiki Toshiharu Yamaguchi Toshifusa Nakajima Hiroshi Takahashi
Publish Date: 2013/05/24
Volume: 6, Issue: 3, Pages: 221-225
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Abstract

A 73yearold woman underwent esophagogastroduodenoscopy EGD at a local hospital which revealed a flat elevated lesion approximately 15 mm in diameter in the posterior wall of the lower gastric body At our hospital a repeat EGD and biopsy led to a diagnosis of moderately dysplastic adenoma The patient requested endoscopic submucosal dissection ESD Histopathology revealed a gastric adenoma with negativity for tumor at the vertical margin however the horizontal margin was positive for cancer with an undifferentiated carcinoma surrounding the adenoma EGD was repeated and a discolored area was found around the ESD scar Biopsy revealed an undifferentiated carcinoma Laparoscopic distal gastrectomy was performed and postoperative histopathology also revealed an undifferentiated carcinoma 50 mm in diameter surrounding the ESD scar this lesion was an undifferentiated adenocarcinoma that was colocalized with and spread out to surround the original adenoma This case is important for consideration of the pattern of development and progression of superficial spreading gastric cancer

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