Paper Search Console

Home Search Page About Contact

Journal Title

Title of Journal: Interdiscip Sci Comput Life Sci

Search In Journal Title:

Abbravation: Interdisciplinary Sciences: Computational Life Sciences

Search In Journal Abbravation:

Publisher

International Association of Scientists in the Interdisciplinary Areas

Search In Publisher:

DOI

10.1007/s00296-005-0602-1

Search In DOI:

ISSN

1867-1462

Search In ISSN:
Search In Title Of Papers:

Can we predict blood brain barrier permeability of

Authors: Rajnish Kumar Anju Sharma Rajesh Kumar Tiwari
Publish Date: 2013/06/06
Volume: 5, Issue: 2, Pages: 95-101
PDF Link

Abstract

An ideal neurotherapeutics agent for central nervous system CNS molecular targets should cross Blood Brain Barrier BBB whereas peripherally acting agent should not cross BBB to avoid CNS related side effects Hence prediction of BBB permeability index has been proved to be an efficient tool for drug discovery and development Various experimental and computational approaches are being used in recent past for the prediction of BBB permeability and they have been successful up to some extent However the accuracy and authenticity of these methods have been under question The current review article attempts to answer a vital question that is can we predict BBB permeability using computational approaches

Keywords:

References

.
Search In Abstract Of Papers:
Other Papers In This Journal:
  1. Understanding the Interactions of High-Mobility Group of Protein Domain B1 with DNA Adducts Generated by Platinum Anticancer Molecules Using In Silico Approaches
  2. Exon skipping event prediction based on histone modifications
  3. A Structure–Activity Relationship Study of Imidazole-5-Carboxylic Acid Derivatives as Angiotensin II Receptor Antagonists Combining 2D and 3D QSAR Methods
  4. Flavonoids as Multi-target Inhibitors for Proteins Associated with Ebola Virus: In Silico Discovery Using Virtual Screening and Molecular Docking Studies
  5. Snore related signals processing in a private cloud computing system
  6. The Calculations and Simulation Testing on the Elastic Modulus of Wheat
  7. In silico Identification of Ergosterol as a Novel Fungal Metabolite Enhancing RuBisCO Activity in Lycopersicum esculentum
  8. Change in Glutenin Macropolymer Secondary Structure in Wheat Sourdough Fermentation by FTIR
  9. Structural Interactions of Curcumin Biotransformed Molecules with the N-Terminal Residues of Cytotoxic-Associated Gene A Protein Provide Insights into Suppression of Oncogenic Activities
  10. Discussion on microcosmic derivation of biological golden section phenomena from DNA geometric structure and snow flower generation
  11. Online Fault Diagnosis for Biochemical Process Based on FCM and SVM
Search Result: