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Title of Journal: Neurosurg Rev

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Abbravation: Neurosurgical Review

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Springer Berlin Heidelberg

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DOI

10.1007/bf00602613

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1437-2320

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Current status of bone graft options for anterior

Authors: Anthony Minh Tien Chau Lileane Liang Xu Johnny HoYin Wong Ralph Jasper Mobbs
Publish Date: 2013/06/07
Volume: 37, Issue: 1, Pages: 23-37
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Abstract

Anterior cervical discectomy and fusion ACDF and anterior lumbar interbody fusion ALIF are common surgical procedures for degenerative disc disease of the cervical and lumbar spine Over the years many bone graft options have been developed and investigated aimed at complimenting or substituting autograft bone the traditional fusion substrate Here we summarise the historical context biological basis and current best evidence for these bone graft options in ACDF and ALIFChau et al submit a review article entitled “Current status of bone graft options for anterior interbody fusion of the cervical and lumbar spine” The authors present a comprehensive review of bone graft options in anterior spinal surgery Despite a lack of original content this article has good clinical application can help direct appropriate treatment and may provide direction for future research and development The best bone graft option is not known despite thousands of anterior spinal fusions performed annually This article independently summarizes each graft and includes a literature review basic scientific evidence and financial cost for each graft option The authors should be congratulated for their workIn this review Chau et al give an overview on anterior interbody fusion of the cervical and lumbar spine by paying special attention to the different options for bone grafts Due to wellknown problems at the donor site the use of autografts is declining parallel to the expanding variety of alternative options including osteogenic osteoconductive osteoinductive and osteopromotive grafts Noteworthy is that almost all studies reported a considerably high rate of fusion which is nicely outlined in the overview tables Moreover besides the very important information on the underlying biology of the different graft types data are provided on the existing level of evidence In conclusion this review offers highly useful data for every spinal surgeon and its publication is therefore welcomed

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