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Title of Journal: Inflamm Bowel Dis

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Gender and Location of CRC in IBDImplications for Surveillance Protocols

Authors: Kwah, Joann, Ditelberg, Jeremy S., Farraye, Francis A.,

Publish Date: 2013/03/01
Volume: 19, Issue:3, Pages: E44-E46
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Patients with longstanding and extensive ulcerative colitis (UC) and Crohn's disease of the colon have an increased risk of developing colorectal cancer (CRC). A meta-analysis published in 2001 including 116 studies from around the world reported the risk of CRC in patients with UC as 2% after 10 years, 8% after 20 years, and 18% after 30 years of disease.1 Data from a 30-year prospective surveillance program in the UK published in 2004 reported a lower risk of CRC in patients with UC of 2.5% at 20 years, 7.6% at 30 years, and 10.8% at 40 years.2 While this suggests that the risk of developing CRC is lower than previously thought, CRC is still a significant concern for patients with UC.



citation_title=Progression of low-grade dysplasia in ulcerative colitis: effect of colonic location; citation_journal_title=Gastrointest Endosc; citation_year=2011; citation_volume=74; citation_pages=1087-1093;

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