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Title of Journal: J Thromb Thrombolysis

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Abbravation: Journal of Thrombosis and Thrombolysis

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Springer US

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DOI

10.1002/9781444345254.ch2

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1573-742X

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Evaluation of the Alere Ddimer test for point of

Authors: Johanna HelmerssonKarlqvist Bo Karlsson Annika Fredriksson Anders Larsson
Publish Date: 2014/01/01
Volume: 38, Issue: 2, Pages: 250-252
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Abstract

The primary care regularly sees patients that have symptoms that could be due to thromboembolic diseases It would be valuable to be able to rule out deep venous thrombosis or pulmonary embolism using Wells score and a negative Ddimer testing already at the primary care unit This requires a validated Ddimer assay suitable for primary care use We compared Ddimer results obtained with the new point of care analyzer Alere Triage® and the central hospital laboratory STAR Evolution analyzer from the same patient samples n = 102 We also calculated the total coefficient of variation CV for the Alere method The two methods showed a good linear correlation R2 = 0977 and a slope of 0975 CV for the Alere Ddimer method was well below 10  The study shows that the Alere Ddimer assay and the central laboratory standard assay show similar results We suggest that the Alere Ddimer assay could be used in primary care in combination with Wells score to reduce referrals to the emergency unit

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