Journal Title
Title of Journal: Curr Rev Musculoskelet Med
|
Abbravation: Current Reviews in Musculoskeletal Medicine
|
|
|
|
|
|
|
|
Authors: Shinichi Yoshiya Aman Dhawan
Publish Date: 2015/09/15
Volume: 8, Issue: 4, Pages: 457-466
Abstract
Among the surgical options for large fullthickness chondral injuries cellbased therapy has been practiced and its satisfactory outcomes have been reported One area that appears promising is cellbased therapies utilizing stem cells Various tissues within the human body contain mesenchymal stem cells MSCs from where these can be harvested These include bone marrow adipose synovium peripheral blood and umbilical cord In this article both preclinical animal studies and clinical studies dealing with the use of MSCs for cartilage repair of the knee are reviewed Majority of the clinical papers have shown promising results however there are a limited number of studies of high evidence level Clinical significance of the stem cell therapy as compared to other surgical options as well as optimization of the procedure in terms of cell type and delivery method is still to be determined
Keywords:
.
|
Other Papers In This Journal:
|