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Title of Journal: Clin Oral Invest

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Abbravation: Clinical Oral Investigations

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Springer Berlin Heidelberg

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DOI

10.1007/bf01766141

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1436-3771

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Facial asymmetry quantitative evaluation in oculoauriculovertebral spectrum

Authors: Renzo Manara, Giovanni Schifano, Davide Brotto, Rodica Mardari, Sara Ghiselli, Antonio Gerunda, Cristina Ghirotto, Stefano Fusetti, Katherine Piacentile, Renato Scienza, Mario Ermani, Alessandro Martini,

Publish Date: 2015/11/18
Volume: 20, Issue:2, Pages: 219-225
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Abstract

Facial asymmetries in oculoauriculovertebral spectrum (OAVS) patients might require surgical corrections that are mostly based on qualitative approach and surgeon’s experience. The present study aimed to develop a quantitative 3D CT imaging-based procedure suitable for maxillo-facial surgery planning in OAVS patients.Thirteen OAVS patients (mean age 3.5 ± 4.0 years; range 0.2–14.2, 6 females) and 13 controls (mean age 7.1 ± 5.3 years; range 0.6–15.7, 5 females) who underwent head CT examination were retrospectively enrolled. Eight bilateral anatomical facial landmarks were defined on 3D CT images (porion, orbitale, most anterior point of frontozygomatic suture, most superior point of temporozygomatic suture, most posterior-lateral point of the maxilla, gonion, condylion, mental foramen) and distance from orthogonal planes (in millimeters) was used to evaluate the asymmetry on each axis and to calculate a global asymmetry index of each anatomical landmark. Mean asymmetry values and relative confidence intervals were obtained from the control group.OAVS patients showed 2.5 ± 1.8 landmarks above the confidence interval while considering the global asymmetry values; 12 patients (92 %) showed at least one pathologically asymmetric landmark. Considering each axis, the mean number of pathologically asymmetric landmarks increased to 5.5 ± 2.6 (p = 0.002) and all patients presented at least one significant landmark asymmetry.Modern CT-based 3D reconstructions allow accurate assessment of facial bone asymmetries in patients affected by OAVS. The evaluation as a global score and in different orthogonal axes provides precise quantitative data suitable for maxillo-facial surgical planning.This study had been approved by the ethic committee and was performed in accordance with the ethical standards laid down in the 1964 Declaration of Helsinki and its later amendments. All details that might disclose the identity of the subjects under study have been omitted. Informed consent was obtained from all OAVS patients included in the study; the controls were retrieved from our PACs. As in our country no consent is required for the retrospective analysis of exams, controls did not provide an informed consent.


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