Journal Title
Title of Journal:
|
|
|
|
|
|
|
|
|
|
Authors: Sylvie Abel André Cabié
Publish Date: 2016
Volume: , Issue: , Pages: 1-17
Abstract
Chikungunya virus CHIKV is an emerging alphavirus transmitted to humans by Aedes mosquitoes CHIKV infection is most often symptomatic and the symptoms last from a few days to several years Experts in France have defined three clinical stages acute stage from the first day on which the first symptoms appear D1 up to day 21 D21 postacute stage from D21 to the end of the third month and chronic stage after 3 months In the acute stage a highgrade fever occurs suddenly along with inflammatory arthralgia and arthritis with periarticular edema and sometimes severe pain Other typical symptoms are myalgia headache backache macular to maculopapular rash and lymphadenopathy Atypical and severe manifestations can occur such as maternal–neonatal transmission in viremic women during childbirth Infected neonates exhibit severe manifestations in 50 of cases So far no specific therapeutic agent to treat infected persons is available and the treatment is symptomatic The main characteristic of the postacute stage is the persistence or the occurrence of multiple and polymorphic manifestations dominated by inflammatory manifestations An accurate semiotic analysis allows defining the diagnostic workup that determines the optimization of treatment In the postacute stage the objective of treatment is to relieve the patient of pain and inflammation and to limit the consequences of the inflammatory process The treatment is primarily based on analgesics and nonsteroidal antiinflammatory drugs The benefit of physical medicine depends on lesion assessment and the disease’s overall impact pain autonomy quality of life The expected benefits are pain relief preserving the range of motion and muscle tone In the chronic stage the diagnostic approach consists of qualifying the nosology of each patient according to the presence or absence of inflammatory symptoms Chronic inflammatory rheumatisms CIR are different from musculoskeletal disorders MSD The former has the most severe functional prognosis the latter are by far the most frequent 95 The management of postchikungunya CIR with or without joint destruction systematically requires the advice of a rheumatologist at best in the context of a multidisciplinary meeting The management of MSD persisting after 3 months is based on the same principles as the management of postacute presentations
Keywords:
.
|
Other Papers In This Journal:
|