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Springer, Cham

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10.1002/food.19720160710

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MicroRNAs and Hepatocellular Carcinoma

Authors: Aldo Cavallini,

Publish Date: 2016
Volume: , Issue:, Pages: 121-137
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Abstract

Genomic studies have demonstrated that many portions of the human genome do not encode conventional protein-coding genes, but encode biologically active noncoding RNA species. One class of such small noncoding RNA is microRNA (miRNA), comprised of a group of well-conserved, small RNA molecules (21-23 nucleotides) that can up- or down-regulate gene expression in normal and abnormal cellular activities by base pairing with 3′ untranslated regions (3′ UTRs) of target messenger RNA (mRNA) [1].


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