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Title of Journal: Clin Oral Invest

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Abbravation: Clinical Oral Investigations

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Springer Berlin Heidelberg

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Short-term changes on C-reactive protein (CRP) levels after non-surgical periodontal treatment in systemically healthy individuals

Authors: André Barbisan de Souza, Rogério T. P. Okawa, Cléverson O. Silva, Maurício G. Araújo,

Publish Date: 2016/04/12
Volume: 21, Issue:1, Pages: 477-484
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Twenty-two patients with chronic periodontitis (test group) and 22 periodontally healthy individuals (control group), both groups without any systemic disorder or potential confounding factors, were included in the study. At baseline, periodontal clinical variables and CRP levels were obtained in both groups. In the test group, oral hygiene instruction and scaling and root planning were carried out; then, after 60 days, periodontal clinical variables and CRP levels were reevaluated.The baseline CRP level in the test group was significantly higher than the corresponding value in the control group (1.98 ± 1.55 vs. 1.26 ± 1.05 mg/L; p 3 mg/L).The authors thank the Biostatistician Alfa I. Yansane, PhD, from the Oral Health Policy and Epidemiology Department–Harvard School of Dental Medicine, for the supervision on the statistical analyses, and also Mr. Antonio C. Correa for the meticulous overall manuscript revision.All procedures performed in this study involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards. The study protocol was submitted, reviewed, and approved by the local ethical committee of the State University of Maringá (241/2009).



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