Authors: Lauren N Bell Richard L Berg John R Schmelzer Hong Liang Joseph J Mazza Rajan Kanth Christopher L Bray Calixto B Zaldivar Steven H Yale
Publish Date: 2016/08/26
Volume: 43, Issue: 1, Pages: 31-37
Abstract
Superficial vein thrombosis SVT may be associated with complications such as venous thromboembolism VTE and recurrent SVT The purpose of this study was to explore risk factors among patients with a first isolated episode of SVT index SVT involving upper and lower extremities and to estimate the prevalence of VTE complications within 1 year of index SVT Retrospective chart review of electronic records at Marshfield Clinic in Wisconsin identified 381 subjects with a first isolated SVT diagnosis male/female 170/211 median age 594 years Patients were stratified based on whether they did n = 44 115 or did not n = 337 885 experience VTE complications and whether they did n = 25 66 or did not n = 356 934 experience pulmonary embolism PE and/or deep vein thrombosis DVT within 1 year of index SVT There were 49 complications among 44 patients these included DVT n = 18 367 propagation of SVT n = 18 367 PE n = 9 184 new SVT at different location n = 3 61 and recurrent SVT n = 1 20 Univariate analysis of all VTE complications identified seven potential risk factors and similar analysis of PE/DVT complications identified eight potential risk factors with six common risk factors identified in both analyses Multivariate analysis identified indwelling venous catheter 30 days prior to SVT p = 0044 cancer history with treatment in the previous year p = 0001 and nonsurgical trauma 7 days prior to SVT p 0001 as independent risk factors for PE/DVT complications Independent risk factors identified in the current study may convey greater risk for VTE complications especially PE/DVT following an initial isolated SVT episode
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