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Title of Journal: Sci Eng Ethics

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Abbravation: Science and Engineering Ethics

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Springer Netherlands

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DOI

10.1016/j.apcatb.2016.11.018

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1471-5546

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Print Me an Organ Ethical and Regulatory Issues E

Authors: Frederic Gilbert Cathal D O’Connell Tajanka Mladenovska Susan Dodds
Publish Date: 2017/02/09
Volume: 24, Issue: 1, Pages: 73-91
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Abstract

Recent developments of threedimensional printing of biomaterials 3D bioprinting in medicine have been portrayed as demonstrating the potential to transform some medical treatments including providing new responses to organ damage or organ failure However beyond the hype and before 3D bioprinted organs are ready to be transplanted into humans several important ethical concerns and regulatory questions need to be addressed This article starts by raising general ethical concerns associated with the use of bioprinting in medicine then it focuses on more particular ethical issues related to experimental testing on humans and the lack of current international regulatory directives to guide these experiments Accordingly this article 1 considers whether there is a limit as to what should be bioprinted in medicine 2 examines key risks of significant harm associated with testing 3D bioprinting for humans 3 investigates the clinical trial paradigm used to test 3D bioprinting 4 analyses ethical questions of irreversibility loss of treatment opportunity and replicability 5 explores the current lack of a specific framework for the regulation and testing of 3D bioprinting treatmentsWe would like to thank Science Engineering Ethics anonymous reviewers and editors for their insightful comments As well the Brocher Foundation Dr Frederic Gilbert is the recipient of an Australian Research Council Discovery Early Career Researcher Award project number DE150101390 Funding from the Australian Research Council Centre of Excellence Scheme Project Number CE 140100012 is gratefully acknowledged

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Other Papers In This Journal:
  1. Climate Change, Responsibility, and Justice
  2. Declaration of Conflicts of Interest in Networking Era: Raising the Bar
  3. Ethical Considerations for Volunteer Recruitment of Visual Prosthesis Trials
  4. Uninformed Consent: An Offshoot of Illiteracy and Ignorance
  5. Ethics Teaching in Higher Education for Principled Reasoning: A Gateway for Reconciling Scientific Practice with Ethical Deliberation
  6. Implementing the Netherlands Code of Conduct for Scientific Practice—A Case Study
  7. Breaking the Cyber-Security Dilemma: Aligning Security Needs and Removing Vulnerabilities
  8. Defining Risk, Motivating Responsibility and Rethinking Global Warming
  9. Ethical Challenges with Welfare Technology: A Review of the Literature
  10. Authorship: Few Myths and Misconceptions
  11. A Matter of Accuracy. Nanobiochips in Diagnostics and in Research: Ethical Issues as Value Trade-Offs
  12. Sabine Roeser, Rafaela Hillerbrand, Per Sandin, Martin Peterson (eds): Handbook of Risk Theory: Epistemology, Decision Theory, Ethics, and Social Implications of Risk
  13. Are the Votes of Ethics Committees in Germany for the Protection of Clinical Study Trial Subjects “Sovereign Acts?”
  14. Engineering Social Justice into Traffic Control for Self-Driving Vehicles?
  15. Piecing Together the Elephant: Public Engagement on Nanotechnology Challenges
  16. Managerial Preferences in Relation to Financial Indicators Regarding the Mitigation of Global Change
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