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Title of Journal: Arch Orth Traum Surg

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Abbravation: Archives of orthopaedic and traumatic surgery

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Springer Berlin Heidelberg

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DOI

10.1007/978-1-4302-4051-8

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1434-3916

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Methicillin induced drugfever during treatment fo

Authors: Haim Stein Mervyn Shapiro Joseph Lowe
Publish Date: 1983/09/01
Volume: 102, Issue: 1, Pages: 23-27
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Abstract

High dose intravenous methicillin therapy is a common form of treatment for post traumatic acute osteomyelitis and septic arthritis with positive staphylococcus aureus cultures A high and spiking fever persisting in the face of adequate antibiotic therapy presents a difficult diagnostic dilemma in such patientsIn seven patients methicillin induced drug fever was found to be the cause of such as persisting pyrexia inspite of an adequate antibiotic regime This diagnosis must be established by a cautious clinical evaluation and by a careful elimination of all other causes for fever Upon discontinuation of methicillin the body temperature reverted to normal within 24hDurch Methicillin verursachtes Fieber wird bei solchen Patienten beschrieben Die richtige Diagnose kann durch sorgfältige Untersuchung der klinischen Zeichen festgestellt werden Wird die Methicillin Therapie eingestellt so geht das Fieber in 24h auf normale Werte zurück


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