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Title of Journal: Int J Mater Form

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Abbravation: International Journal of Material Forming

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Springer-Verlag

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DOI

10.1007/s00228-006-0106-2

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1960-6214

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Tubular scaffold for vascular tissue engineering a

Authors: V La Carrubba F Carfì Pavia V Brucato
Publish Date: 2010/06/12
Volume: 3, Issue: 1, Pages: 567-570
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Abstract

A critical obstacle in tissue engineering is the inability to maintain large masses of living cells upon transfer from the in vitro culture conditions into the host in vivo Capillaries and the vascular system are required to supply essential nutrients including oxygen remove waste products and provide a biochemical communication “highway” Another goal in this research field is the possibility to tune the biodegradability of the scaffold After implantation the scaffold has to be gradually replaced by cells and extra cellular matrix and it is crucial that this replacement takes place with an appropriate dynamics A premature degradation in fact could lead to a collapse of the structure as the newly generated tissue could not have reached yet the suitable mechanical properties Conversely a long degradation time could brake or completely interrupt the development of the new tissue In this work PLLAPLA scaffolds for vascular tissue engineering were produced by dipcoating via Diffusion Induced Phase Separation DIPS technique Pure PLA scaffolds and 75/25 PLA/PLLA scaffolds were obtained and characterized No homogeneous scaffolds were obtained by using a 50/50 PLLA/PLA blend

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  2. Research on Friction during Hot Deformation of Al-Alloys at High Strain Rate
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