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Title of Journal: Oncol Rev

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Abbravation: Oncology Reviews

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Springer Milan

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10.1016/j.acap.2011.02.011

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1970-5565

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Paclitaxel induced chronic fibrosing interstitial

Authors: Renata Ferrarotto Guilherme Schetino Daniela Freitas Vera Capelozzi Paulo M Hoff
Publish Date: 2010/04/08
Volume: 4, Issue: 2, Pages: 101-106
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Abstract

Pulmonary toxicity is rarely associated with paclitaxel chemotherapy and its mechanism is not well known This report describes one patient with pancreatic adenocarcinoma metastatic neuroendocrine lowgrade pancreatic tumor and a concomitant stage I nonsmall cell lung cancer NSCLC who also developed lifethreatening paclitaxelinduced chronic fibrosing interstitial pneumonitis Giving the gravity of the condition and the notwellestablished treatment physicians should be aware of the possibility of chronic fibrosing interstitial lung disease during the course of paclitaxel containing regimens in patients who present with respiratory symptoms


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