Cardioplegia and ventricular late potentials in ca

Authors: N Schütz J A Romand N D Yanez M M Treggiari K Bendjelid

Publish Date: 2011/09/20

Volume: 25, Issue: 4, Pages: 269-

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Abstract

Ventricular late potentials LP recording with signalaveraged electrocar diogram allow identifying patients at risk of sudden death and ventricular tachycardia Cardiac surgery with cardiopulmonary bypass CPB could predispose to the development of myocardial ischemia related to imperfect cardioplegia To the best of our knowledge no study investigated the protection of cardioplegia and CPB regarding the occurrence of LP in patients without previous myocardial infarction and undergoing cardiac surgeryIn 61 elective patients scheduled for cardiac surgery involving CPB signalaveraged electrocar diogram was performed the day before and 24–48 h after the surgery The electrodes were positioned according to Frank’s orthogonal derivations Twenty five patients were excluded because of poor quality signals leaving 36 patients age 64 ± 14 available for the analyses An abnormal signalaveraged electrocardiogram was considered when ≥2 of the recorded indexes were present McNemar’s tests were performed on the dichotomized values to investigate differences in prepost scoresThe mean CPB duration was of 110 ± 57 min Patients scheduled for cardiac surgery do not exhibited LP after CPB no significant difference in prepost CPB scores P = NS The probability of a patient with a negative score transitioning to a positive score was 023 P = NS

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