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Title of Journal: Biomech Model Mechanobiol

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Abbravation: Biomechanics and Modeling in Mechanobiology

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Springer-Verlag

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DOI

10.1016/0267-3649(93)90045-o

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1617-7940

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A semistochastic cellbased formalism to model th

Authors: F J Vermolen A Gefen
Publish Date: 2011/03/26
Volume: 11, Issue: 1-2, Pages: 183-195
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Abstract

We consider the movement and viability of individual cells in cell colonies Cell movement is assumed to take place as a result of sensing the strain energy density as a mechanical stimulus The model is based on tracking the displacement and viability of each individual cell in a cell colony Several applications are shown such as the dynamics of filling a gap within a fibroblast colony and the invasion of a cell colony Though based on simple principles the model is qualitatively validated by experiments on living fibroblasts on a flat substrateThis article is published under an open access license Please check the Copyright Information section for details of this license and what reuse is permitted If your intended use exceeds what is permitted by the license or if you are unable to locate the licence and reuse information please contact the Rights and Permissions team


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