Desloratadine a guide to its use in allergic diso

Authors: Katherine A LysengWilliamson

Publish Date: 2014/01/03

Volume: 30, Issue: 2, Pages: 35-41

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Abstract

Oral desloratadine an effective and welltolerated secondgeneration antihistamine is indicated for the oncedaily treatment of the symptoms of allergic rhinitis and urticaria in paediatric and adult patients It has a favourable pharmacological profile which is characterized by a rapid onset of action efficacy that persists over the 24h dosing period a lack of corrected QT interval prolongation a lack of CNS effects including sedation and a lack of clinically relevant drug and food interactions It has documented therapeutic efficacy in the treatment of allergic rhinitis with or without coexisting asthma and urticaria The overall tolerability profile of desloratadine is similar to that of placeboThe manuscript was reviewed by R Janknegt Orbis Medical Centre SittardGeleen The Netherlands P Matoulková Faculty of Pharmacy in Hradec Králové Charles University in Prague Hradec Králové Czech Republic S Saluja Consultant in Internal Medicine Saran Ashram Agra IndiaThe preparation of this review was not supported by any external funding During the peer review process the manufacturer of the agent under review was offered an opportunity to comment on the article Changes resulting from comments received were made by the authors on the basis of scientific and editorial merit

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