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Title of Journal: Forensic Sci Med Pathol

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Abbravation: Forensic Science, Medicine, and Pathology

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Springer US

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DOI

10.1002/anie.201206202

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1556-2891

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Acute hemorrhagic leukoencephalomyelitis in a man

Authors: Indira D Kitulwatte Patrick J H Kim Michael S Pollanen
Publish Date: 2015/07/08
Volume: 11, Issue: 3, Pages: 416-420
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Abstract

We report a case of acute hemorrhagic leukoencephalomyelitis in a man with viral myocarditis A 48yearold previously healthy male was found dead in his locked apartment At autopsy he was found to be malnourished and his lungs showed gross evidence of bilateral pneumonia with abscess formation and bullous emphysema Multiple petechial hemorrhages were observed in the brain and mainly involved white matter in the cerebral hemispheres including the corpus callosum and internal capsule as well as the cerebellum brainstem and spinal cord Microscopy of the brain and spinal cord revealed perivenular hemorrhages central microthrombi in venules with fibrin exudation into the subcortical white matter and early perivenular demyelination associated with scanty mixed cellular infiltrates Other microscopic features included widespread diffuse viral myocarditis extensive suppurative bronchopneumonia and chronic bronchitis This case illustrates the death of a man with a rare fatal disease associated with two other potentially lethal diseases The case also illustrates the importance of a holistic approach when determining the cause of death especially when there are competing causes of death


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