Journal Title
Title of Journal: Curr Psychiatry Rep
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Abbravation: Current Psychiatry Reports
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Authors: Ghassen Saba Albert Moukheiber Antoine Pelissolo
Publish Date: 2015/04/01
Volume: 17, Issue: 5, Pages: 36-
Abstract
Repetitive transcranial magnetic stimulation rTMS and transcranial direct current stimulation tDCS are noninvasive brain stimulation methods that became widely used as therapeutic tools during the past two decades especially in cases of depression and schizophrenia Low frequency rTMS and cathodal effect of tDCS inhibits cortical functioning while high frequency and anodal effect of tDCS have the opposite effect Prolonged and repetitive application of either methods leads to changes in excitability of the human cortex that outlast the period of stimulation Both rTMS and tDCS induce functional changes in the brainmodulating neural activity at cortical level This paper reviews rTMS and tDCS effects in clinical trials for obsessivecompulsive disorder OCD Low frequency rTMS particularly targeting the supplementary motor area and the orbital frontal cortex seems to be the most promising in terms of therapeutic efficacy while older studies targeting the prefrontal dorsal cortex were not as successful tDCS clearly needs to be investigated in large scale and sufficiently powered randomized control studies From a general point of view these noninvasive techniques hold promise as novel therapeutic tools for OCD patients
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