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Title of Journal: Front Biol

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Abbravation: Frontiers in Biology

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Higher Education Press

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10.1007/978-3-0348-0837-8_2

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1674-7992

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Drosophila seizure disorders genetic suppression

Authors: Arunesh Saras Laura E Simon Harlan J Brawer Richard E Price Mark A Tanouye
Publish Date: 2016/04/25
Volume: 11, Issue: 2, Pages: 96-108
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Abstract

Various Drosophila models of human disease have recently received increased interest The main goal is to uncover the fundamental biological basis for human pathology taking advantage of the power of Drosophila genetics This review examines a set of Drosophila seizuresensitive mutations that model human seizure disorders especially epilepsy Also described is a novel set of mutations that act as seizuresuppressors that ameliorate epilepsy phenotypes in double mutant combinations


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