Journal Title
Title of Journal: Biospektrum
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Publisher
Springer Berlin Heidelberg
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Authors: RosaEva Hüttl Andrea B Huber
Publish Date: 2016/02/17
Volume: 22, Issue: 1, Pages: 19-21
Abstract
Andrea Huber Biologiestudium an der Universität Basel Schweiz 2000 Promotion an der ETH Zürich Schweiz 2000–2005 Postdoc an der Johns Hopkins University Baltimore MD USA 2006–2013 Gruppenleiterin am Helmholtz Zentrum München Seit 2013 Leitung der Koordinationsstelle des BernsteinNetzwerks Computational Neuroscience in FreiburgDuring development of the central nervous system CNS proliferation cell fate designation and patterning decisions are tightly regulated by interdependent networks of key transcriptional regulators We propose a novel aspect of how Pax6 not only utilizes its modular structure to perform distinct functions but also employs individual subdomains thus generating a new level of complexity for transcriptional regulation by one single transcription factor in dorsoventral and rostrocaudal neural tube patterning
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