Journal Title
Title of Journal: Chromosoma
|
|
|
Publisher
Springer-Verlag
|
|
|
|
|
|
Authors: Helen G Tempest Darren K Griffin
Publish Date: 2005/04/08
Volume: 114, Issue: 4, Pages: 295-299
Abstract
Our understanding of the incidence and origin of chromosome abnormalities in human preimplantation embryos is very limited due to the necessary ethical constraints involved in studying such material and the limited data ultimately produced Several studies have addressed this issue however using techniques such as interphase fluorescence in situ hybridisation modified Gbanding preparation and the use of singlecell comparative genomic hybridisation CGH This review discusses the use of these techniques in assessing chromosome abnormalities in this the earliest of human developmental stages In addition the prospects for the clinical use of CGH are discussed
Keywords:
.
|
Other Papers In This Journal:
|