The ISWI remodeler in plants protein complexes b

Authors: Dongjie Li Jie Liu Wu Liu Guang Li Zhongnan Yang Peng Qin Lin Xu

Publish Date: 2017/02/17

Volume: 126, Issue: 3, Pages: 365-373

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Abstract

Imitation Switch ISWI is a member of the ATPdependent chromatin remodeling factor family whose members move or restructure nucleosomes using energy derived from ATP hydrolysis ISWI proteins are conserved in eukaryotes and usually form complexes with DDT DNAbinding homeobox and different transcription factorsdomain proteins Here we review recent research on ISWI in the model plant Arabidopsis thaliana AtISWI AtISWI forms complexes with AtDDTdomain proteins many of which have domain structures that differ from those of DDTdomain proteins in yeast and animals This might suggest that plant ISWI complexes have unique roles In vivo studies have shown that AtISWI is involved in the formation of the evenly spaced pattern of nucleosome arrangement in gene bodies—this pattern is associated with high transcriptional levels of genes In addition AtISWI and the AtDDTdomain protein RINGLET RLT are involved in many developmental processes in A thaliana including meristem fate transition and organ formation Studies on the functions of AtISWI may shed light on how chromatin remodeling functions in plants and also provide new information about the evolution of ISWI remodeling complexes in eukaryotesThe authors apologize for references not cited due to space limitations This work was supported by grants from the National Natural Science Foundation of China 31630007/31422005/81471667 National Basic Research Program of China 973 Program 2012CB910503 the Key Research Program of the Chinese Academy of Sciences QYZDBSSWSMC010 and Youth Innovation Promotion Association CAS 2014241

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