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Abbravation: The Journal of Headache and Pain

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BioMed Central

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10.1002/9780470756997.ch21

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1129-2377

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Understanding clinical trials in migraine

Authors: P TfeltHansen
Publish Date: 2006/04
Volume: 7, Issue: 2, Pages: 101-
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Abstract

The following points are covered in this review 1 How a randomised clinical trial in migraine is performed The whole process from idea to publication of an article is reviewed 2 How to understand a paper on clinical trials in migraine The aim of the study design of study efficacy measures and presentation of results are reviewed The aim of the study is often stated vaguely and it is suggested to look at the power calculations in order to understand the aim of the study The aims and the results of the trial programmes of the triptans are reviewed Results of the study should be presented with 95CI 3 How to understand meta–analyses in migraine Relationship between meta–analyses and head–to–head comparative trials is reviewed and it is concluded that head–to–head comparisons remain the “golden standard” with metaanalyses as a useful supplementBy submitting a comment you agree to abide by our Terms and Community Guidelines If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate Please note that comments may be removed without notice if they are flagged by another user or do not comply with our community guidelines


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Other Papers In This Journal:

  1. “Comorbidity” between epilepsy and headache/migraine: the other side of the same coin!
  2. SUNCT syndrome responding absolutely to steroids in two cases with different etiologies
  3. Psychological and social stressors and psychiatric comorbidity in patients with migraine without aura from headache centers in Italy: a comparison with tension-type headache patients
  4. Headache and cognitive profile in children: a cross-sectional controlled study
  5. Demographic, clinical and comorbidity data in a large sample of 1147 patients with migraine in Mexico City
  6. Genetics of migraine and pharmacogenomics: some considerations
  7. Published and not fully published double-blind, randomised, controlled trials with oral naratriptan in the treatment of migraine: a review based on the GSK Trial Register
  8. Clinical and descriptive analysis of chronic daily headaches
  9. Headache and neck pain: Gabapentin as a possible treatment
  10. Tinnitus in postherpetic neuralgia
  11. Narcotic analgesics for acute migraine in the emergency room: are we meeting Headache Societies' guidelines?
  12. G.F. d’Acquapendente tabulae pictae on the nervous system
  13. Guidelines for telematic second opinion consultation on headaches in Europe: on behalf of the European Headache Federation (EHF)
  14. Drug consumption in medication overuse headache is influenced by brain-derived neurotrophic factor Val66Met polymorphism
  15. Ehlers–Danlos syndrome: correlation with headache disorders in a young woman
  16. Commentary to ‘Comorbidity in Finnish migraine families’
  17. Medication–overuse headache: pathophysiological insights

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