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Title of Journal: Eur Spine J

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Abbravation: European Spine Journal

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Springer-Verlag

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10.1016/0002-9394(49)91437-3

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1432-0932

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The effect of prevertebroplasty tumor ablation us

Authors: Henry Ahn Payam Mousavi Lee Chin Sandra Roth Joel Finkelstein Alex Vitken Cari Whyne
Publish Date: 2007/04/20
Volume: 16, Issue: 8, Pages: 1171-1178
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Abstract

A biomechanical study comparing simulated lytic vertebral metastases treated with laserinduced thermotherapy LITT and vertebroplasty versus vertebroplasty alone To investigate the effect of tumor ablation using LITT prior to vertebroplasty on biomechanical stability and cement fill patterns in a standardized model of spinal metastatic disease Vertebroplasty in the metastatic spine is aimed at reducing pain but is associated with risk of cement extravasation in up to 10 Six pairs of freshfrozen cadaveric thoracolumbar spinal motion segments were tested in axial compression intact with simulated metastases and following percutaneous vertebroplasty with or without LITT Canal narrowing under load pattern of cement fill load to failure and LITT temperature and pressure generation were collected In all LITT specimens cement filled the defect without extravasation The canal extravasation rate was 33 in specimens treated without LITT LITT and vertebroplasty yielded a trend toward improved posterior wall stability P = 0095 as compared to vertebroplasty alone Moderate rises in temperature and minimal pressure generation was seen during LITT In this model elimination of tumor by LITT facilitates cement fill enhances biomechanical stability and reduces the risk of cement extravasation

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