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Title of Journal: Arch Immunol Ther Exp

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Abbravation: Archivum Immunologiae et Therapiae Experimentalis

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Birkhäuser-Verlag

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DOI

10.1007/s10658-009-9439-x

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1661-4917

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Positive and negative regulatory mechanisms in hig

Authors: Kristy Roth WeiMin Chen TongJun Lin
Publish Date: 2008/12/01
Volume: 56, Issue: 6, Pages: 385-399
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Abstract

Mast cells are important effector cells in allergic inflammatory reactions The aggregation of the highaffinity IgE receptor FcεRI on the surface of mast cells initiates a complex cascade of signaling events that ultimately leads to the release of various mediators involved in allergic inflammation and anaphylactic reactions The release of these mediators is tightly controlled by signaling pathways that are propagated through the cell by specific phosphorylation and dephosphorylation events These events are controlled by protein kinases and protein phosphatases which either positively or negatively regulate the propagation of the signal through the cell This review summarizes the role of both positive and negative regulators of FcεRIinduced mast cell activation


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Other Papers In This Journal:

  1. Primary Biliary Cholangitis Associated with Skin Disorders: A Case Report and Review of the Literature
  2. Regulation of cytokine transcription in the context of chromatin
  3. All roads lead to Rome: pathways of NKT cells promoting asthma
  4. Dual Peripheral Actions of Immune Cells in Neuropathic Pain
  5. Functions of Cancer-Derived Extracellular Vesicles in Immunosuppression
  6. Transplantology: Challenges for Today
  7. Effects of IFN-β1a and IFN-β1b treatment on the expression of cytokines, inducible NOS (NOS type II), and myelin proteins in animal model of multiple sclerosis
  8. Matrix Metalloproteinases and Their Inhibitors in Chronic Obstructive Pulmonary Disease
  9. Pre-Pregnancy Levels of Peripheral Natural Killer Cells as Markers for Immunomodulatory Treatment in Patients with Recurrent Miscarriage
  10. Comparison of two methods used for monitoring low-copy cytomegalovirus infection in a patient with chronic myeloid leukemia after unrelated umbilical cord blood transplantation
  11. Pro-Cognitive Properties of the Immunomodulatory Polypeptide Complex, Yolkin, from Chicken Egg Yolk and Colostrum-Derived Substances: Analyses Based on Animal Model of Age-Related Cognitive Deficits
  12. Immune Modulation in Xenotransplantation
  13. IRF4 selectively controls cytokine gene expression in chronic intestinal inflammation
  14. Sjögren’s syndrome: An old tale with a new twist
  15. Gene Polymorphisms of Novel Immunotolerant Molecule BTLA: Distribution of Alleles, Genotypes and Haplotypes in Polish Caucasian Population
  16. Biological Agents Database in the Armed Forces

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