RETRACTED ARTICLE Microenvironment characterizati

Authors: XiHua Sui QingFang Zha MingBo Wu YanSheng Guo

Publish Date: 2009/07/30

Volume: 52, Issue: 8, Pages: 1120-1127

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Abstract

The compatible carbonsilicon complex materials originated from precursor diglycerylsilane DGS and sugarmodified silane N3triethoxysilylpropylgluconamide GLS have gained substantial popularity by demonstrating admirable properties to stabilize entrapped biomolecules The microenvironment inside these materials especially the distribution of sugar moieties inside the matrix which is likely the most critical factor determining compatibility of these materials still remains unclear To deeply investigate the biocompatibility mechanism of these materials we have adopted two different preparation routes for these materials by introducing GLS into the starting DGS sol stage but things are different after the DGS gel is formed A fluorescence probe rhodamine 6G is introduced herein in the DGS sol to monitor the distribution of GLS moieties as well as the evolution of the microenvironment inside resulting materials All in all the findings demonstrated that the timing of GLS addition plays a critical role in controlling the evolution of the inner structure of materials suggesting that this factor provides a promising route to tune the properties of the resulting materialsSupported by the National Natural Science Foundation of China Grant No 20876176 Scientific Research Foundation for the Returned Overseas Chinese Scholars by the State Education Ministry Key Project of Chinese Ministry of Education Grant No 109100 Doctoral Project of Shandong Province Grant No 2008BS09013 Research Foundation of Key Laboratory of Carbon Materials Institute of Coal Chemistry CAS Grant No KFJJ0506 and Natural Science Foundation of Shandong Province Grant No Q2007B02

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