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Title of Journal: J Chem Sci

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Abbravation: Journal of Chemical Sciences

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Springer-Verlag

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DOI

10.1002/jobm.19810210213

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0973-7103

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Palladiumcatalysed ortho arylation of acetanilide

Authors: GuoZhen Zhang ChengQun Chen XinHua Feng GuoSheng Huang
Publish Date: 2010/04/30
Volume: 122, Issue: 2, Pages: 149-155
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Abstract

The palladiumcatalysed direct arylation of acetanilides by using CH activation methodology has been demonstrated Several acetanilides were coupled with aryl iodides in the presence of 10 mol of PdOAc2 1·0 equiv of CuOTf2 and 0·6 equiv of Ag2O to afford the corresponding products in moderate to excellent yields The results showed that the amount of Ag2O was important for this protocol

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