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Title of Journal: Arch Orthop Trauma Surg

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Abbravation: Archives of Orthopaedic and Trauma Surgery

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Springer-Verlag

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1434-3916

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Effects of lowenergy NMR on posttraumatic osteoar

Authors: Hendrik Jansen Sönke P Frey Jürgen Paletta Rainer H Meffert
Publish Date: 2010/11/10
Volume: 131, Issue: 6, Pages: 863-868
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Abstract

Following transection of the anterior cruciate ligament of both knees in 24 skeletally mature New Zealand White rabbits we observed different stages of osteoarthrosis OA 6 and 12 weeks postoperatively Animals were randomized into four groups Group 1 eight animals was treated after 6 weeks by NMR magnetic field 20–40 G interference field 235 mT 100 kHz MBST®Device MedTec Germany with 1 h of treatment for seven consecutive days Group 2 was treated in the same pattern after 12 weeks The shamoperated groups 3 and 4 received no treatment Seven days after the last treatment OA was macroscopically graded and hyaline cartilage of the load bearing area was evaluated histologically according to the Mankin scaleMacroscopically there was less OA in group 1 p  001 but did not reveal significance in group 2 p = 011 compared to the sham groups There was no significant difference in the Mankin score in both of the treated groups compared to the control groups group 1 p = 036 group 2 p = 081The results showed some beneficial macroscopic effect in mild OA with less macroscopic OA signs in the treated animals but without a histological effect in the Mankin scale There was no effect found in the pattern later OA On behalf of these results NMR for the treatment of posttraumatic OA cannot be recommended at this point of time

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