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Title of Journal: Arch Orthop Trauma Surg

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Abbravation: Archives of Orthopaedic and Trauma Surgery

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Springer-Verlag

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1434-3916

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No difference in mortality between cemented and un

Authors: O Talsnes F Hjelmstedt A H Pripp O Reikerås O E Dahl
Publish Date: 2013/03/27
Volume: 133, Issue: 6, Pages: 805-809
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Abstract

Laboratory and human mechanical studies indicated that chemical substances in bone cement had toxic and prothrombotic effects Impaction of cement added a mechanical trauma to the reaming and broaching procedure and contributed to a substantial local and systemic thrombin generation Case reports and materials have indicated bone cement as the immediate trigger of cardiorespiratory and vascular dysfunction occasionally fatal and described as the bone cement implantation syndrome In spite of this knowledge bone cement has gained popularity and is widely used for prosthesis fixation possibly due to a lack of clinical evidence supporting the basic science indicating bone cement as a mortality risk factorWe find no difference in mortality between cemented and uncemented hemiprosthesis up to 1 year HR 077 95  CI 051–118 p = 0233 However statistically significant reduced operation time and blood loss were found in the noncemented group mean difference of 13 min 95  CI 4–22 p = 0004 and 92 ml 95  CI 3–181 p = 0043 respectivelyThe authors are grateful to the two orthopaedic department chiefs Tore Kristiansen and Amund Rudlang who have organized all local logistics and eagerly participated in all investigator meetings Yvonne Bell Eli Lundemo Øieren and Tor Arne Valle have provide us with valuable assistance and help with study practicalities which have been of great importance for the team Vladimir Milic has been our faithful and skilled data expert that has developed and followed up on the study database Financial support The author has received the Charnley Grant from Orthomedic AS and financial support from Centre of Medical Science Education and Innovation Innlandet Hospital Trust Elverum Norway

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  9. Clinical and radiological outcomes after stabilisation of complex intra-articular fractures of the distal radius with the volar 2.4 mm LCP
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  12. Angular and sliding stable antegrade nailing (Targon PH) for the treatment of proximal humeral fractures
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