Mechanical Thrombectomy Compared to LocalIntraart

Authors: M Möhlenbruch M Seifert T Okulla U Wüllner D R Hadizadeh M Nelles S Greschus K Wilhelm H H Schild T Klockgether H Urbach

Publish Date: 2011/10/05

Volume: 22, Issue: 2, Pages: 141-147

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Abstract

The aim of the study was to examine the effects of mechanical thrombectomy using the Solitaire stent in patients with thromboembolic occlusions of the intracranial carotid artery bifurcation carotid T or middle cerebral artery MCA and to compare the results with a historical cohort treated with local intraarterial thrombolysis using urokinaseThe time intervals from stroke onset to treatment recanalization rates occlusion sites recanalization times and functional outcomes on the modified Rankin scale at 3 months in 25 patients treated with the Solitaire stent between 2010 and 2011 were evaluated The data were compared with those of a historical cohort of 62 patients treated with local intraarterial thrombolysis between 1992 and 2001A total of 15 out of 25 60 patients treated with mechanical thrombectomy and 25 out of 62 40 treated with local intraarterial thrombolysis achieved a modified Rankin score of  £ 2 p = 007 Occlusion sites intervals from stroke onset to treatment and rates of parenchymal hematomas 3 out of 25 12 versus 8 out of 62 13 were similar in both cohorts while the recanalization rate was significantly higher 22 out of 25 88 versus 33 of 62 53 in the mechanical thrombectomy group p £ 001

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