Prediction of nearfuture HbA1c levels using glyca

Authors: Masafumi Koga Jun Murai Hiroshi Saito Soji Kasayama

Publish Date: 2012/05/12

Volume: 3, Issue: 4, Pages: 197-201

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Abstract

We previously reported an equation predicting nearfuture HbA1c levels using glycated albumin GA levels before and after treatment for diabetes In this study we investigated whether the prediction of HbA1c levels is useful to decide on the necessity of additional treatment for diabetesThis study consisted of 11 patients with type 2 diabetes with HbA1c levels ≥84  without any medical treatment Glimepiride administration was started at a dose of 1 mg/day and the HbA1c level at 14 weeks was predicted by GA levels before and 2 weeks after the administration When the predicted HbA1c level at 14 weeks was 80  the treatment was continued Otherwise the dose of glimepiride was raised or metformin was addedIn seven patients whose treatment was unchanged the predicted HbA1c level at 14 weeks was 71 ± 05  which was similar to the measured HbA1c level at 14 weeks 71 ± 06  In four patients who were given additional treatment the predicted HbA1c level at 14 weeks was 94 ± 10  significantly higher than the measured HbA1c at 14 weeks 75 ± 07 

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