Authors: Umut Celikyurt Aysen Agacdiken Tayfun Sahin Guliz Kozdag Ahmet Vural Dilek Ural
Publish Date: 2012/06/12
Volume: 35, Issue: 2, Pages: 215-218
Abstract
Sixtysix consecutive patients mean age 57 ± 13 years 42 men undergoing CRT were included in the study Hematological parameters and echocardiographic parameters were measured before and 6 months after CRT An echocardiographic response to CRT was defined as a ≥15 relative increase in left ventricular ejection fraction after 6 monthsAfter 6 months of CRT 47 71 patients were responders High baseline RDW levels were found in 11 23 and 10 52 patients in responders and nonresponders respectively p 005 In nonresponders RDW at 6 months was significantly high compared to baseline RDW 171 ± 2 vs 19 ± 29 p 0001 There was not any significant change in RDW after CRT in responders 16 ± 16 vs 155 ± 14 p 005 In multivariate analysis significant associates of response to CRT were evaluated adjusting for QRS width QRS morphology age New York Heart Association functional class hemoglobulin and RDW level Baseline RDW level was the only predictor of response to CRT odds ratio 1435 95 confidence interval 1059–1945 p = 0020
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