Authors: Susumu Tao Yasuteru Yamauchi Shingo Maeda Hiroyuki Okada Tetsuo Yamaguchi Nobuhiro Hara Yuji Konishi Tomoyuki Umemoto Takamichi Miyamoto Tohru Obayashi Kenzo Hirao Mitsuaki Isobe
Publish Date: 2013/12/10
Volume: 39, Issue: 2, Pages: 103-109
Abstract
In 81 AF patients undergoing pulmonary vein isolation PVI we injected 20 mg of ATP before PVI and recorded triggering sites of the AF induced We also injected 20 mg of ATP in 44 patients receiving ablation for atrioventricular reciprocating tachycardia AVRTATP provoked AF in 24 296 of the 81 PVI patients and atrial ectopic beats in a further 48 593 The trigger site of the AF was in the PV and the right atrium in 22 917 and 2 patients respectively In 14 of those 24 patients spontaneous AF arose from the same triggering site as the ATPinduced AF In the 48 patients with ATPprovoked ectopic beats spontaneous AF arose from the same site in 13 Conversely among the 34 patients demonstrating spontaneous AF initiation AF or ectopic beats were provoked by ATP from the same site in 14 412 and 13 patients 382 respectively ATP provoked AF in only 2 45 of the AVRT patients In summary ATP provoked AF or atrial ectopic beats in 889 of PVI patients 361 of whose triggering sites matched that of the spontaneous AF while 794 of spontaneous AF trigger sites matched ATPprovoked AF or ectopic beat sites
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