Correlation between some hematological parameters

Authors: A Hosseini F Namazi A Oryan S Nazifi

Publish Date: 2013/05/15

Volume: 39, Issue: 2, Pages: 155-161

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Abstract

The present study was undertaken to investigate correlation between some hematological parameters acute phase proteins and immunoglobulins in the experimentally infected goats with Besnoitia caprae from the time of infection till 360 days post infection DPI Six male goats approximately 12–16 months old were inoculated subcutaneously with approximately 13 × 108 bradyzoites of B caprae and blood samples were collected at weekly intervals from the jugular vein of the goats Total leukocyte count and differential leukocyte counts were determined Acute phase proteins APPs including serum amyloid A SAA haptoglobin Hp fibrinogen and ceruloplasmin were undertaken at weekly intervals We evaluated an enzymelinked immunosorbent assay ELISA using a somatic antigen of bradyzoite to detect antiB caprae antibodies in caprine sera Cysts were present in the skin biopsies of the distal parts of the leg of the infected goats from 28 DPI From 30 to 360 DPI results showed that the APPs concentrations including SAA Hp fibrinogen and ceruloplasmin were enhanced in the serum of infected goats However there were some variation in hematological parameters the differences were not significant with those of the normal values Some variations were seen in the levels of specific antibodies against this parasite and they had correlation with some hematological parameters and acutephase proteinsThe authors would like to thank the members of the research committee for providing financial support They would like to thank Dr M AnsariLari for her assistance in statistical evaluations We also thank Mr M Rahsepar for his technical assistance in hematological evaluations

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