Authors: Kiran Yadav Shalini Aggarwal Kamlesh Verma
Publish Date: 2013/12/17
Volume: 64, Issue: 3, Pages: 169-174
Abstract
A variety of biological biochemical and biophysical markers implicated in the pathophysiology of preeclampsia during the last two decades have instigated the growing interest in this study to include both βhCG and lipid profile studies in the early second trimester as early predictors of pregnancyinduced hypertension Early identification of atrisk women may help in taking timely preventive and curative management to prevent or delay complications associated with pregnancyinduced hypertensionA prospective study was performed on 120 patients attending the outpatient department of the Obstetrics and Gynaecology of the Maharaja Agrasen Hospital All the patients were screened for serum βhCG and serum lipid profile in their early second trimester 14–20 weeks and followed up till their delivery Comparative studies of serum βhCG and serum lipid profile were performed between those who remain normotensive group I and those who developed pregnancyinduced hypertension group IITG total cholesterol VLDL and LDL values for those women who developed PIH group II were significantly higher than those who remain normotensive group I with p value of 005 which is statistically significant HDL and βhCG values for group II were not higher than those in group I with p value 005 which is statistically insignificantMaternal lipid profile in second trimester is very good noninvasive test which can be used for prediction of pregnancyinduced hypertension before its clinical onset However there is no correlation between maternal serum βhCG and pregnancyinduced hypertension
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