Paper Search Console

Home Search Page About Contact

Journal Title

Title of Journal: Glycoconj J

Search In Journal Title:

Abbravation: Glycoconjugate Journal

Search In Journal Abbravation:

Publisher

Springer US

Search In Publisher:

DOI

10.1007/3-7643-7704-6_4

Search In DOI:

ISSN

1573-4986

Search In ISSN:
Search In Title Of Papers:

Antithrombinbinding oligosaccharides structural

Authors: Marco Guerrini Pierre A J Mourier Giangiacomo Torri Christian Viskov
Publish Date: 2014/08/22
Volume: 31, Issue: 6-7, Pages: 409-416
PDF Link

Abstract

Heparinantithrombin interaction is one of the most documented examples of heparin/protein complexes The specific heparin sequence responsible for the binding corresponds to a pentasaccharide sequence with an internal 3Osulfated glucosamine residue Moreover the position of the pentasaccharide along the chain as well as the structure of the neighbor units affects the affinity to antithrombin The development of separation and purification techniques in conjunction with physicochemical approaches mostly NMR allowed to characterize several structural variants of antithrombinbinding oligosaccharides both in the free state and in complex with antithrombin The article provides an overview of the studies that lead to the elucidation of the mechanism of interaction as well as acquiring new knowledge in heparin biosynthesis

Keywords:

References

.
Search In Abstract Of Papers:
Other Papers In This Journal:
  1. Glycan microarrays for screening sialyltransferase specificities
  2. Exquisite binding specificity of Sclerotium rolfsii lectin toward TF-related O-linked mucin-type glycans
  3. XXI International Symposium on Glycoconjugates
  4. Neutral N-glycan patterns of the gastropods Limax maximus , Cepaea hortensis , Planorbarius corneus , Arianta arbustorum and Achatina fulica
  5. Complex N -glycans or core 1-derived O -glycans are not required for the expression of stage-specific antigens SSEA-1, SSEA-3, SSEA-4, or Le Y in the preimplantation mouse embryo
  6. Photons to illuminate the universe of sugar diversity through bioarrays
  7. Sialylation in protostomes: a perspective from Drosophila genetics and biochemistry
  8. Obituary: Hal Dixon
  9. Versatile strategy for the synthesis of biotin-labelled glycans, their immobilization to establish a bioactive surface and interaction studies with a lectin on a biochip
  10. Chemical characterization of milk oligosaccharides of the koala ( Phascolarctos cinereus )
  11. Saccharomyces cerevisiae Gpi2, an accessory subunit of the enzyme catalyzing the first step of glycosylphosphatidylinositol (GPI) anchor biosynthesis, selectively complements some of the functions of its homolog in Candida albicans
Search Result: