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Title of Journal: Immunol Res

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Abbravation: Immunologic Research

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Springer US

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DOI

10.1007/s00481-004-0291-4

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1559-0755

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Importance of intestinal microenvironment in devel

Authors: Anna Bazsó Péter Szodoray Gábor Sütő Yehuda Shoenfeld Gyula Poór Emese Kiss
Publish Date: 2014/11/19
Volume: 61, Issue: 1-2, Pages: 172-176
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Abstract

A strong connection between spondylarthropathies and inflammatory bowel diseases IBD is well established About 10–15  of IBD are associated with different forms of spondylarthritis Arthritis can be manifested as axial peripheral form or both The primary functions of the gastrointestinal tract are digestion and absorption of nutrients electrocytes and maintenance of water homoeostasis The anatomic and functional lesions could lead to the development of IBD based on molecular mimicry and bystander effects The mechanism of the macromolecules is uptaken may affect intestinal and extraintestinal manifestation in genetically susceptible individuals by gutassociated lymphoid tissue the interplay between innate and adaptive immunity and the neuroendocrine network

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