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Title of Journal: Brain Struct Funct

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Abbravation: Brain Structure and Function

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Springer Berlin Heidelberg

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DOI

10.1007/bf02769982

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ISSN

1863-2661

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Homotopic reciprocal functional connectivity betwe

Authors: Nuria Lacuey Bilal Zonjy Emine S Kahriman Ahmad Marashly Jonathan Miller Samden D Lhatoo Hans O Lüders
Publish Date: 2015/05/21
Volume: 221, Issue: 5, Pages: 2695-2701
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Abstract

The aim of this study was to investigate functional connectivity between right and left insulae in the human brain We studied a patient with implanted depth electrodes for epilepsy surgery evaluation with stereotactically placed symmetric depth electrodes in both insulae Bipolar 1 Hz electrical stimulation of the right and left posterior short gyri in the anterior insula evoked responses in the contralateral insular structures These responses showed a latency of 8–24 ms This report demonstrates for the first time bidirectional homotopic and heterotopic functional connectivity between right and left anterior insulae The short latency of the evoked responses suggests mono or oligosynaptic connections most likely via the corpus callosum

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