Assessment of hematologic parameters before and af

Authors: Bruno Ramos Chrcanovic Guilherme Lacerda de Toledo Márcio Bruno Figueiredo Amaral Antônio Luís Neto Custódio

Publish Date: 2015/08/18

Volume: 20, Issue: 1, Pages: 35-43

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Abstract

Fiftythree patients were prospectively evaluated and divided into groups based on the surgical procedure and sex predictor variables Hemoglobin red blood cells hematocrit and platelet were the primary outcome variables operation time the secondary outcome and the patients’ age and weight the other variables Trial registration NCT02364765 US National Institutes of Health clinicaltrialsgovThere was statistically significant difference between all hematologic parameters before and after surgery for both men and women and for all surgical groups There was a positive correlation between operative time and the decrease in of the hematologic parameters Linear regression analysis suggested that the Hb values decrease 0083  for every minute increase in the operation time and 0066 0066 and 0010  for RBC Hct and platelet count respectively There was a negative correlation between weight and all hematologic parameters Correlations between age and hematologic parameters were not statistically significant Almost all correlations between age weight sex and the surgery group and the hematologic parameters were considered as very weak Only one patient was transfusedThis study involves human subjects Ethical approval was acquired from the Department of Morphology Ethics Committee Institute of Biological Sciences Federal University of Minas Gerais Belo Horizonte Brazil Clinical trial registration number NCT02364765 clinicaltrialsgov Patient permission was acquired All authors have viewed and agreed to the submission

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