Authors: Cornelio Blus Giulio Giannelli Serge SzmuklerMoncler Germano Orru
Publish Date: 2016/12/06
Volume: 21, Issue: 1, Pages: 41-48
Abstract
A cohort of 18 consecutive patients has been treated for MRONJ they involved 20 sites 15 in the mandible and five in the maxilla Surgical removal of the necrotic areas and debridement was performed with a powerful piezoelectric surgery device max 90 W in combination with antibiotherapyWe hypothesize that healing of all treated sites might have resulted from the synergic effect of bone ablation biofilm alteration and antibiotic administration Biofilm alteration might have permitted a better access of antibiotics to the involved germs These encouraging results warrant further studies on the use of ultrasonic surgery to treat MRONJ patients in order to confirm or refute the hypothesized effect
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